DE.Init on IIS6 works intermittencly

[SR]

HELP !!!

I have an old ASP web site that runs since 1998 (IIS3, 4,5). It use
DataEnviroment stuff :-(

Now on IIS6 after a couple of hours of use this line get in error:

DE.Init(Application("DE"))

Microsoft VBScript runtime error '800a0005'
Invalid procedure call or argument
/test.asp, line 25

All the rights, connection, global.asa, dataenvinroment.asa, etc are ok...

If you hit after the error F5 maybe it runs ok or maybe it goes still in
error
After an IISRESET things get better, but after few hours it comes again...
(memory leaks ?)

Thanks in advance
Sandro