"System.IO.IOException: The device is not ready asp.net"

[SystemDown]

I have an ASP.NET application that works perfectly in its virtual
folder on IIS 6 (win2003). I made an exact copy of the app that points
to another database of the same type in a new website on the same
server with a different port number for training purposes. Everytime I
access the training app I get this error:

"System.IO.IOException: The device is not ready asp.net"

Apparently this occurs when the app tries to access the user defined
parameters in the web.config file. I tried putting the app in a sub
folder of the original website and I got the same error. All folders
have full access rights for "everyone".

I'm totally stumped right now and any help would be appriciated.

 

[SkippyFire]

Are you using encryption or some sort of logging?

Are you using encryption or some sort of logging? Maybe you have an encryption key stored in a file somewhere... or a log file that doesn't exist... or some other type of input/output that is dependent on the environment?